The most common symptom of vaginal cancer is painless vaginal bleeding, which means you may not feel vaginal cancer at all. Less commonly, you may experience pain in your pelvis, painful urination or discomfort related to constipation.
If you receive a vaginal cancer diagnosis, it’s important to have an honest discussion with your provider about the type of cancer, if it’s spread, and what your treatment options are. Your prognosis will depend on multiple factors. Your provider is your best resource for explaining what this diagnosis means for you.
In the meantime, establishing a support network that includes family members, friends, current cancer patients and cancer survivors is an essential part of your care plan, too. The American Cancer Society can connect you with cancer support groups. Speak to a counselor to process your diagnosis. Getting your emotional needs met is as important as the clinical care you receive.
Vaginal cancer is a rare cancer that occurs in your vagina — the muscular tube that connects your uterus with your outer genitals. Vaginal cancer most commonly occurs in the cells that line the surface of your vagina, which is sometimes called the birth canal.
While several types of cancer can spread to your vagina from other places in your body, cancer that begins in your vagina (primary vaginal cancer) is rare.
A diagnosis of early-stage vaginal cancer has the best chance for a cure. Vaginal cancer that spreads beyond the vagina is much more difficult to treat.
Products & Services Assortment Women's Health Products from Mayo Clinic Store Show more products from Mayo Clinic Symptoms Female reproductive organs Female reproductive systemOpen pop-up dialog box Early vaginal cancer may not cause any signs and symptoms. As it progresses, vaginal cancer may cause signs and symptoms such as:
Unusual vaginal bleeding, for example, after intercourse or after menopause Watery vaginal discharge A lump or mass in your vagina Painful urination Frequent urination Constipation Pelvic pain When to see a doctor See your doctor if you have any signs and symptoms related to vaginal cancer, such as abnormal vaginal bleeding. Since vaginal cancer doesn't always cause signs and symptoms, follow your doctor's recommendations about when you should have routine pelvic exams.
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Can Vaginal Cancer Be HereditaryIt's not clear what causes vaginal cancer. In general, cancer begins when healthy cells acquire a genetic mutation that turns normal cells into abnormal cells.
Healthy cells grow and multiply at a set rate, eventually dying at a set time. Cancer cells grow and multiply out of control, and they don't die. The accumulating abnormal cells form a mass (tumor).
Cancer cells invade nearby tissues and can break off from an initial tumor to spread elsewhere in the body (metastasize).
Vaginal cancer is divided into different types based on the type of cell where the cancer began. Vaginal cancer types include:
Vaginal squamous cell carcinoma, which begins in the thin, flat cells (squamous cells) that line the surface of the vagina, and is the most common type Vaginal adenocarcinoma, which begins in the glandular cells on the surface of your vagina Vaginal melanoma, which develops in the pigment-producing cells (melanocytes) of your vagina Vaginal sarcoma, which develops in the connective tissue cells or muscles cells in the walls of your vagina Risk factors Factors that may increase your risk of vaginal cancer
Increasing age. Your risk of vaginal cancer increases as you age. Most people who are diagnosed with vaginal cancer are older than 60.
Atypical cells in the vagina called vaginal intraepithelial neoplasia. Being diagnosed with vaginal intraepithelial neoplasia (VAIN) increases your risk of vaginal cancer.
With VAIN, cells in the vagina appear different from normal cells, but not different enough to be considered cancer. A small number of those with VAIN will eventually develop vaginal cancer, though doctors aren't sure what causes some cases to develop into cancer and others to remain benign.
VAIN is frequently caused by the sexually transmitted human papillomavirus (HPV), which can cause cervical, vaginal and vulvar cancers, among others. Vaccines that prevent some types of HPV infection are available.
Exposure to miscarriage prevention drug. If your mother took a drug called diethylstilbestrol (DES) while pregnant in the 1950s you may have an increased risk of a certain type of vaginal cancer called clear cell adenocarcinoma.
Other risk factors that have been linked to an increased risk of vaginal cancer include: Multiple sexual partners Early age at first intercourse Smoking HIV infection Complications Vaginal cancer may spread (metastasize) to distant areas of your body, such as your lungs, liver and bones. Prevention There is no sure way to prevent vaginal cancer. However, you may reduce your risk if you: Undergo regular pelvic exams and Pap tests. You can increase the chance that vaginal cancer is discovered early by having routine pelvic exams and Pap tests. When discovered in its earliest stages, vaginal cancer is more likely to be cured. Discuss with your doctor when to begin these tests and how often to repeat them.
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